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In gut mucosa of mild to acute cases of COVID-19 (with IBD as comorbidity), the persistence of SARS-CoV-2 RNA was detected in ~70% PASC patients, whereas the viral nucleocapsid (N) protein was found in ~50% of PASC patients after seven months of post-recovery 278

Two principal mechanisms have been proposed: the classical transferrin-dependent pathway and the transcytosis model ( + is reduced to Fe + , exported into the cytosol by divalent metal transporter 1 (DMT1), and subsequently released across the abluminal membrane via ferroportin 1 (FPN1), followed by re-oxidation through ceruloplasmin before entering the brain parenchyma (172, 173)

doi: 10.1038/s41586-022-05089-y

M.Alonso-AriasR